APPLIKON BIOREACTOR PDF

Applikon is a leading manufacturer of bioreactors 1 to 10, liters in both cell and microbial culture. Applikon supplies laboratory instrumentation to a dynamic worldwide enterprise supplying a broad and diverse line of bioreactor systems. Our autoclavable bioreactor systems are the worldwide industry standard. Not yet a member of BioProcess Online? Register today.

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Applikon Biotechnology is a world leader in developing and supplying advanced bioreactor systems for the production of vaccines, antibodies, tissues, bio-pharmaceuticals, nutraceuticals and biosimilars in the Pharmaceutical industry, as well as enzymes, food, feed, bio-fuel, bio-chemicals and bio-plastics for Industrial Biotechnology.

We can guide you through the whole upstream process, from initial screening up to full-scale production, using the same platform. Applikon Biotechnology proudly promotes an improved Quality of Life. As a world leader in the development and supply of advanced bioreactor systems, Applikon passionately contributes to the Life Sciences. Our goal is to continuously introduce new technologies to the market, covering the spectrum from laboratory scale via pilot plant to production scale.

In addition to advanced cultivation systems, our core business also comprises Process Control and Process Information Management systems. The AppliFlex ST is a fully customizable stirred tank single-use bioreactor. By using 3D printing technology, we can create any head plate configuration that is optimal for your process. With this single-use system there is no risk of cross contamination between runs.

The pre-sterilized, ready-to-use bioreactor makes your life in the lab a lot easier. No more assembling and sterilization before you can start your culture.

No more cleaning after the culture is finished. Save time and costs, execute more runs, and reduce your time-to-market. The AppliFlex ST differentiates from other single-use bioreactors by being a fully customizable stirred tank bioreactor. You can choose, or even design, the type and number of impellers, the number of liquid and gas additions and the type of sparger that are optimal for your process.

The 3D printing production technology guarantees complete reproducibility between the different bioreactors guaranteeing exact and identical conditions between runs. The AppliFlex ST offers the flexibility that you need for your specific bioprocess and is available for both cell culture and microbial applications. The AppliFlex ST can be used as single unit as well as parallel processing systems. The design of the AppliFlex ST is a scale down version of our larger laboratory scale systems guaranteeing an easy scale-up of your process from the mL to the larger volume cultivations.

The single-use system can be exchanged with a multi-use system whenever your process or workflow needs a different approach. The AppliFlex ST features a fully removable topplate for operators to have easy access to the culture. Pouring into downstream processing vessels or other bioreactors has never been this easy. Optionally a closed lid is available which makes the vessel ready for transport, storage or freezing.

Water supply is not required to operate the AppliFlex ST, cooling and heating are done using electric elements, the condenser is cooled electrically as well. No expensive laminar flowhood is needed to operate the system, expect for operator handling. This makes process transfer from the lab to production and from production to the lab very simple. Applikon offers glass autoclavable bioreactors for cell culture applications and glass autoclavable fermentors for microbial culture applications.

The systems are built according to the specific demands of a process using an extensive array of standard components. Because of the modularity and flexibility, the user can always adapt the systems to changed process demands. The stirred tank reactor STR is the most widely used bioreactor type. Glass autoclavable bioreactors and fermentors are available in jacketed and single wall versions in 2, 3, 5, 7, 15 and 20 liter total volume 20 liter only in single wall version.

The worldwide standard for benchtop cultivation. The Applikon Pilot system bioreactor range is divided into a microbial range and a cell culture range of volumes. The main difference between these two lines is the aspect ratio of the bioreactors.

The microbial systems have an aspect ratio of 3. The small footprint guarantees that the minimal amount of floor space is occupied by the system. All systems are fully documented for cGMP usage and are supplied with an extensive documentation package to support validation. A wide range of standard modules and standard packs is available to customize the systems to your specific demands. A wide range of add-on packs is available. The standard packs include pressure control, weight control, double gas inlet lines, CIP modules, biomass sensors, perfusion systems and much more.

Applikon offers a choice of ez-Control and i-Control process control systems. All i-Control systems support automated Sterilization and Cleaning procedures.

Solutions for upstream bioprocessing in Pharma and Industrial Biotechnology. Read More. Single-use bioreactors. Multi-use bioreactors. Stainless steel bioreactors.

About Applikon Biotechnology. Disposable bioreactors Designed on Demand. AppliFlex ST. Glass autoclavable bioreactors Applikon offers glass autoclavable bioreactors for cell culture applications and glass autoclavable fermentors for microbial culture applications. Stainless Steel Bioreactors The Applikon Pilot system bioreactor range is divided into a microbial range and a cell culture range of volumes.

Modularity A wide range of standard modules and standard packs is available to customize the systems to your specific demands. Control Applikon offers a choice of ez-Control and i-Control process control systems. Contact us.

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About Applikon Biotechnology

To get in touch with Applikon adds 3L customizable single-use bioreactor to AppliFlex ST family, simply fill out the form below. Subscribe to receive the latest updates from Applikon Biotechnology. Applikon has extended its innovative family of AppliFlex ST customizable single-use bioreactor systems with a three liter version for cell culture applications. The AppliFlex ST is a fully customizable and scalable stirred tank single-use bioreactor that uses 3D printing technology to provide bioreactor design that is uniquely configured to each individual process, including custom impeller design, inlets, outlets and various port connections. Further, it guarantees complete reproducibility between the different customized bioreactors, providing exact identical conditions between runs. AppliFlex ST is designed to be easy to open at end of run to facilitate a simple transfer to downstream processing.

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Applikon adds 3L customizable single-use bioreactor to AppliFlex ST family

Applikon Biotechnology is a world leader in developing and supplying advanced bioreactor systems for the production of vaccines, antibodies, tissues, bio-pharmaceuticals, nutraceuticals and biosimilars in the Pharmaceutical industry, as well as enzymes, food, feed, bio-fuel, bio-chemicals and bio-plastics for Industrial Biotechnology. We can guide you through the whole upstream process, from initial screening up to full-scale production, using the same platform. Applikon Biotechnology proudly promotes an improved Quality of Life. As a world leader in the development and supply of advanced bioreactor systems, Applikon passionately contributes to the Life Sciences. Our goal is to continuously introduce new technologies to the market, covering the spectrum from laboratory scale via pilot plant to production scale.

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Applikon Technology Bioreactors

Applikon provides controllers to satisfy the requirements of bioreactors from laboratory research through production scale applications. Extending the concept of modularity you will be able to find a controller configured to satisfy the most demanding application. All Applikon controllers are CE approved and designed to meet the strictest electromagnetic immunity requirements to provide dependable operation. Two controllers are available to meet your requirements: The i-Control accommodates standardized bioreactor control software based upon industrial standard PLC solutions. The i-Control offers a state of the art controller and actuator console for bioreactor systems of various sizes and volumes.

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Applikon Bioreactor

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